Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development doi: 10.1242/dev.058479.
نویسندگان
چکیده
منابع مشابه
Publisher's Note: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium by El-Hashash et al. Development doi:10.1242/dev.058479.
Publisher's Note: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium by El-Hashash et al. Development This Publisher's Note relates to the article 'Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium' by El-Hashash et al. (doi:10.1242/dev.058479). We have recently bee...
متن کاملEya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium.
Cell polarity, mitotic spindle orientation and asymmetric division play a crucial role in the self-renewal/differentiation of epithelial cells, yet little is known about these processes and the molecular programs that control them in embryonic lung distal epithelium. Herein, we provide the first evidence that embryonic lung distal epithelium is polarized with characteristic perpendicular cell d...
متن کاملRetraction: Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J. Cell. Sci. doi: 10.1242/102848.
The journal is retracting ‘Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium’ by Ahmed H. K. ElHashash, Gianluca Turcatel, Saaket Varma, Mohamed Berika, Denise Al Alam and David Warburton (2012). J. Cell Sci. 125, 4036-4048 (doi: 10.1242/102848). Journal of Cell Science is retracting this article at the request of the institution. The authors have been notifi...
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The airways are conduits that transport atmospheric oxygen to the distal alveolus. Normally, airway mucous cells are rare. However, diseases of the airway are often characterized by mucous metaplasia, in which there are dramatic increases in mucous cell numbers. As the Notch pathway is known to regulate cell fate in many contexts, we misexpressed the active intracellular domain of the mouse Not...
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Although there is accumulated evidence of a role for Notch in the developing lung, it is still unclear how disruption of Notch signaling affects lung progenitor cell fate and differentiation events in the airway epithelium. To address this issue, we inactivated Notch signaling conditionally in the endoderm using a Shh-Cre deleter mouse line and mice carrying floxed alleles of the Pofut1 gene, w...
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ورودعنوان ژورنال:
- Development
دوره 144 20 شماره
صفحات -
تاریخ انتشار 2017